Endometriosis and malignancy: The intriguing relationship

Objective To determine the prevalence and study association of ovarian, uterine, breast cancers with endometriosis. Methods A cross-sectional all women a tissue-proven diagnosis endometriosis postoperatively in tertiary care hospital between January 1, 2010, December 31, 2019, was conducted to coexistent malignancy. Patient details were obtained from electronic clinical records. Univariate analysis followed by multivariate done find independent risk factors associated Results Out 800 patients, 104 (13.0%) found have malignancy: ovarian (50, 6.2%); endometrial (33, 4.1%); synchronous (7, 0.9%); (14, 1.8%). Increasing age (odds ratio [OR] 1.13; 95% confidence interval [CI] 1.09–1.16), higher levels cancer antigen 125 (CA 125) (OR 1.002; CI 1.001–1.005), postmenopausal status 6.2; 2.0–19.2), duration over 5 years 4.7; 2.5–9.0), endometriomas larger than 8 cm (area under curve 0.83) predictive Conclusion Endometriosis is an increased endometrial, age, status, CA 125, endometrioma, long-standing disease are factors.